[Pouchitis--pathophysiology and therapy].

Authors:
A J Kroesen, S Schreiber, H J Buhr
Year of publication:
2002
Volume:
127
Issue:
11
Issn:
0044-409X
Journal title abbreviated:
ZBL CHIR
Journal title long:
Zentralblatt für Chirurgie
Impact factor:
0.638
Abstract: 
Ulcerative colitis can be cured with a reasonable quality of life by the complete excision of the colorectum and construction of an ileoanal pouch. The cure is incomplete since there is a certain incidence of a so called pouchitis. Pouchitis occurs with a frequency of 36 %. A single episode of a pouchitis can be cured easily, but in 8-32 % the concerned patients develop a chronic pouchitis. There are many signs that pouchitis might be a remanifestation of ulcerative colitis. This article gives an overview on the actual state of pathophysiology, pathogenesis and therapy of this disease. Apart of that the surgical aspects of the disease are described.