The Research Training Group (RTG) Genes, Environment and Inflammation is a joint and highly interdisciplinary effort from the Kiel University and the University of Lübeck. Both institutions are actively participating in the DFG excellence cluster “Inflammation at Interfaces”. A group of scientists working together at these institutions initiated this Research Training Group. Together, they stand for expertise, innovative approaches and the belief that interdisciplinary research will be the most promising. Speaker of the RTG is Prof. Dr. Andre Franke, Institute of Clinical Molecular Biology.
The next doctoral researcher's generation will start in October 2018.
Starting every April of a year (until 2020) the RTG will offer two scholarships for excellent medical students for a fixed term of one year. Interested candidates may contact the PIs directly.
Doctoral researchers obtain access to a wide variety of different in vitro and in vivo methods and theoretical computational approaches such as subsequent data mining and bioinformatic analyses. Optimal infrastructures are available at the two universities in Kiel and Lübeck, not least the currently built Center of Molecular Life Sciences (“Zentrum für Molekulare Biowissenschaften”, ZMB) and the nationally unique Comprehensive Centers for Inflammation Medicine (CCIM).
Within the RTG the scientists study the environmental influences responsible for the development of complex, chronic diseases. Moreover, they systematically examine the previously understudied interplay between the (micro-)environment and predisposing genetic factors. The research is based on a highly interdisciplinary and technology-driven approach and involves scientists from many different countries. The results will help to define novel pathophysiological trigger factors and aid the development of innovative therapeutic approaches. Much of the work is based on mouse models, as these warrant a homogeneous and controlled modification of the environment; for example, different diets can be fed and the impact on the gut microbiome and inflammatory conditions measured. Having access to patients, the RTG memebers will validate their findings in the human model system, too. Another focus of the Research Training Group is on the gut microbiome, an organ-like system that recently received a lot of attention due to its relevance in metabolism, health and disease, and due also to the avenue that it may be modified by means of pre- and probiotics.