Stephan Schneiders

Doctoral Researcher

Research Interest

In this project we will analyse the T cell reactivity of FDRs and treatment naïve early disease patients against candidate microbes identified in previous and ongoing studies. For that purpose, we will carry out T cell reactivity screenings against identified colitogenic microbes and other potential antigens using our established antigen-reactive T cell enrichment (ARTE) technology in order to characterise the responsive disease-relevant T cell populations. The overall aim is to find a direct link between microbial dysbiosis and aberrant immune reaction, and to identify biomarkers and antigens that help to predict and explain the clinical onset and disease course of IBD.