Publications

Institut für Klinische Molekularbiologie der Christian-Albrechts-Universität zu Kiel

2019

The IL-6-neutralizing sIL-6R-sgp130 buffer system is disturbed in patients with type 2 diabetes.
PubMed (PMID: 31237452) | 2019 | American journal of physiology. Endocrinology and metabolism
A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers.
PubMed (PMID: 31331382) | 2019 | Clinical epigenetics
Pseudomonas aeruginosa populations in the cystic fibrosis lung lose susceptibility to newly applied β-lactams within 3 days.
PubMed (PMID: 31355848) | 2019 | The Journal of antimicrobial chemotherapy
Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases.
PubMed (PMID: 31326413) | 2019 | Gastroenterology (New York, N.Y. 1943)
A structured weight loss program increases gut microbiota phylogenetic diversity and reduces levels of Collinsella in obese type 2 diabetics: A pilot study.
PubMed (PMID: 31318902) | 2019 | PloS one
First known case of paediatric inflammatory bowel disease in a western lowland gorilla may be linked to a familial mutation in the MEFV gene.
PubMed (PMID: 31227591) | 2019 | Gut : journal of the British Society of Gastroenterology
Alterations of the bile microbiome in primary sclerosing cholangitis.
PubMed (PMID: 31243055) | 2019 | Gut : journal of the British Society of Gastroenterology
Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis.
PubMed (PMID: 31250469) | 2019 | Alimentary pharmacology & therapeutics
Sustained Clinical Remission With Vedolizumab in Patients With Moderate-to-Severe Ulcerative Colitis.
PubMed (PMID: 30365009) | 2019 | Inflammatory bowel diseases
Secreted frizzled-related protein 5 serum levels in human periodontitis-A nested case-control study.
PubMed (PMID: 30762911) | 2019 | Journal of clinical periodontology
Adjustment of triple shellac coating for precise release of bioactive substances with different physico-chemical properties in the ileocolonic region.
PubMed (PMID: 30991131) | 2019 | International journal of pharmaceutics
Differential genetic and functional background in inflammatory bowel disease phenotypes of a Greek population: a systems bioinformatics approach.
PubMed (PMID: 31249629) | 2019 | Gut pathogens
Liver infiltrating T cells regulate bile acid metabolism in experimental cholangitis.
PubMed (PMID: 31207266) | 2019 | Journal of hepatology : the journal of the European Association for the Study of the Liver
Genetic background of high blood pressure is associated with reduced mortality in premature neonates.
PubMed (PMID: 31201254) | 2019 | Archives of disease in childhood. Fetal and neonatal edition
Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors.
PubMed (PMID: 31444389) | 2019 | Scientific Reports
Copy number variants in lipid metabolism genes are associated with gallstones disease in men.
PubMed (PMID: 31485028) | 2019 | European journal of human genetics
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay.
PubMed (PMID: 31495601) | 2019 | Alzheimer's & dementia
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
PubMed (PMID: 31511532) | 2019 | Nature communications
Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms.
PubMed (PMID: 31521200) | 2019 | Microbiome
Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy.
PubMed (PMID: 31474368) | 2019 | Cell
Effects of Quantification Methods, Isolation Kits, Plasma Biobanking, and Hemolysis on Cell-Free DNA Analysis in Plasma.
PubMed (PMID: 31343271) | 2019 | Biopreservation and biobanking
Editorial: gut microbial profile associated with primary sclerosing cholangitis-what is new and how do we progress from here? Authors' reply.
PubMed (PMID: 31414547) | 2019 | Alimentary pharmacology & therapeutics
Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition.
PubMed (PMID: 31399369) | 2019 | Cell host & microbe
Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.
PubMed (PMID: 31145742) | 2019 | PLoS genetics / Public Library of Science
Efficacy and Safety of Adalimumab by Disease Duration: Analysis of Pooled Data From Crohn's Disease Studies.
PubMed (PMID: 30753371) | 2019 | Journal of Crohn's & colitis : international journal devoted to inflammatory bowel diseases
Evaluation of variable selection methods for random forests and omics data sets.
PubMed (PMID: 29045534) | 2019 | Briefings in bioinformatics
Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes.
PubMed (PMID: 30916990) | 2019 | FASEB journal
Inter-chromosomal coupling between vision and pigmentation genes during genomic divergence.
PubMed (PMID: 30833758) | 2019 | Nature ecology & evolution
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.
PubMed (PMID: 30573655) | 2019 | Annals of the rheumatic diseases
Atopic Dermatitis Is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis.
PubMed (PMID: 30641038) | 2019 | Journal of investigative dermatology
Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms.
PubMed (PMID: 30661054) | 2019 | Gut : journal of the British Society of Gastroenterology
Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.
PubMed (PMID: 30678657) | 2019 | BMC cardiovascular disorders
Analysis of long non-coding RNA and mRNA expression in bovine macrophages brings up novel aspects of Mycobacterium avium subspecies paratuberculosis infections.
PubMed (PMID: 30733564) | 2019 | Scientific Reports
Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2.
PubMed (PMID: 30709874) | 2019 | Cold Spring Harbor molecular case studies
Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry.
PubMed (PMID: 30692554) | 2019 | Scientific Reports
ZNF133 Is Associated with Infliximab Responsiveness in Patients with Inflammatory Bowel Diseases.
PubMed (PMID: 30851117) | 2019 | Journal of gastroenterology and hepatology
Metastasis of pancreatic cancer: An uninflamed liver micromilieu controls cell growth and cancer stem cell properties by oxidative phosphorylation in pancreatic ductal epithelial cells.
PubMed (PMID: 30930235) | 2019 | Cancer letters
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
PubMed (PMID: 31152163) | 2019 | Nature genetics
Integrating Culture-based Antibiotic Resistance Profiles with Whole-genome Sequencing Data for 11,087 Clinical Isolates.
PubMed (PMID: 31100356) | 2019 | Genomics, proteomics & bioinformatics
Surrogate minimal depth as an importance measure for variables in random forests.
PubMed (PMID: 30824905) | 2019 | Bioinformatics
Antibiotics-induced monodominance of a novel gut bacterial order.
PubMed (PMID: 30658995) | 2019 | Gut : journal of the British Society of Gastroenterology
Mould-reactive T cells for the diagnosis of invasive mould infection-A prospective study.
PubMed (PMID: 31034691) | 2019 | Mycoses : diagnosis, therapy and prophylaxis of fungal diseases : official publ. d. Deutschsprachigen Mykologischen Gesellschaft e.V
The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus.
PubMed (PMID: 30852652) | 2019 | Human genetics
Genome-wide association study of psoriasis in an Egyptian population.
PubMed (PMID: 30921485) | 2019 | Experimental dermatology
Linking pre-existing biorepositories for medical research: the PopGen 2.0 Network.
PubMed (PMID: 30927239) | 2019 | Journal of community genetics
No association between Parkinson disease and autoantibodies against NMDA-type glutamate receptors.
PubMed (PMID: 30984390) | 2019 | Translational neurodegeneration
VarWatch-A stand-alone software tool for variant matching.
PubMed (PMID: 31022234) | 2019 | PloS one
Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy.
PubMed (PMID: 31059154) | 2019 | Movement disorders : official journal of the Movement Disorder Society
Genetic mechanism underlying sexual plasticity and its association with colour patterning in zebrafish (Danio rerio).
PubMed (PMID: 31060508) | 2019 | BMC genomics
Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans.
PubMed (PMID: 30799037) | 2019 | Cell