Publications

Institut für Klinische Molekularbiologie der Christian-Albrechts-Universität zu Kiel

2018

Fungus-Specific CD4 T Cells as Specific Sensors for Identification of Pulmonary Fungal Infections.
PubMed (PMID: 29168073) | 2018 | Mycopathologia / International Mycological Institute
DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis.
PubMed (PMID: 29921915) | 2018 | Nature communications
EVOLUTIONARY DISTANCE PREDICTS RECURRENCE AFTER LIVER TRANSPLANTATION IN MULTIFOCAL HEPATOCELLULAR CARCINOMA.
PubMed (PMID: 29994984) | 2018 | Transplantation
Whole-exome sequencing identifies rare genetic variations in German families with pulmonary sarcoidosis.
PubMed (PMID: 30054724) | 2018 | Human genetics
The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging.
PubMed (PMID: 30087674) | 2018 | Frontiers in immunology
Role of wnt5a in metabolic inflammation in humans.
PubMed (PMID: 30137542) | 2018 | The Journal of clinical endocrinology and metabolism
Small dense LDL cholesterol in human subjects with different chronic inflammatory diseases.
PubMed (PMID: 30143407) | 2018 | Nutrition, metabolism, and cardiovascular diseases : NMCD
Compound heterozygous mutations in IL10RA combined with a complement factor properdin mutation in infantile-onset inflammatory bowel disease.
PubMed (PMID: 30199474) | 2018 | European journal of gastroenterology & hepatology
Genome-wide association meta-analysis of coronary artery disease and periodontitis reveals a novel shared risk locus.
PubMed (PMID: 30209331) | 2018 | Scientific Reports
Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci.
PubMed (PMID: 30218097) | 2018 | European journal of human genetics
IL-17A is functionally relevant and a potential therapeutic target in bullous pemphigoid.
PubMed (PMID: 30219389) | 2018 | Journal of autoimmunity
Mucosal Autoimmunity to Cell-Bound GP2 Isoforms Is a Sensitive Marker in PSC and Associated With the Clinical Phenotype.
PubMed (PMID: 30233574) | 2018 | Frontiers in immunology
A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention.
PubMed (PMID: 30153653) | 2018 | Aging
RNA based individualized drug selection in breast cancer patients without patient-matched normal tissue.
PubMed (PMID: 30190792) | 2018 | Oncotarget
Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.
PubMed (PMID: 30089902) | 2018 | Nature : a weekly illustrated journal of science
Linear isoforms of the long noncoding RNA CDKN2B-AS1 regulate the c-myc-enhancer binding factor RBMS1.
PubMed (PMID: 30108282) | 2018 | European journal of human genetics
The Iceman's Last Meal Consisted of Fat, Wild Meat, and Cereals.
PubMed (PMID: 30017480) | 2018 | CB : current biology : dispatches from the front lines of biology
On a Western diet, APOEɛ4 is associated with low innate immune sensing, but not APOEɛ3.
PubMed (PMID: 29928926) | 2018 | Journal of allergy and clinical immunology
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.
PubMed (PMID: 29880062) | 2018 | Microbiome
Functional abdominal pain and discomfort (IBS) is not associated with faecal microbiota composition in the general population.
PubMed (PMID: 29860240) | 2018 | Gut : journal of the British Society of Gastroenterology
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.
PubMed (PMID: 29795570) | 2018 | PLoS genetics / Public Library of Science
Antigen-specific regulatory T-cell responses against aeroantigens and their role in allergy.
PubMed (PMID: 29858582) | 2018 | Mucosal immunology official journal of the Society for Mucosal Immunology
Candida-Reactive T Cells for the Diagnosis of Invasive Candida Infection-A Prospective Pilot Study.
PubMed (PMID: 29988394) | 2018 | Frontiers in Microbiology
Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus.
PubMed (PMID: 30279286) | 2018 | mBio
Low-Frequency Blood Group Antigens in Switzerland.
PubMed (PMID: 30283273) | 2018 | Transfusion medicine and hemotherapy
Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients.
PubMed (PMID: 30301895) | 2018 | Nature communications
Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data.
PubMed (PMID: 30325587) | 2018 | American journal of medical genetics Part B, Neuropsychiatric genetics
Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea.
PubMed (PMID: 30353760) | 2018 | Scandinavian journal of gastroenterology
Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity.
PubMed (PMID: 30391469) | 2018 | Gastroenterology (New York, N.Y. 1943)
Systems Medicine in Chronic Inflammatory Diseases.
PubMed (PMID: 29669240) | 2018 | Immunity (Cambridge, Mass.)
Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases.
PubMed (PMID: 29748708) | 2018 | International journal of colorectal disease
Reply.
PubMed (PMID: 29750908) | 2018 | Gastroenterology (New York, N.Y. 1943)
A Novel Eukaryotic Denitrification Pathway in Foraminifera.
PubMed (PMID: 30078568) | 2018 | CB : current biology : dispatches from the front lines of biology
Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.
PubMed (PMID: 30209218) | 2018 | Proceedings of the National Academy of Sciences of the United States of America
Grow With the Challenge - Microbial Effects on Epithelial Proliferation, Carcinogenesis, and Cancer Therapy.
PubMed (PMID: 30294304) | 2018 | Frontiers in Microbiology
Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice.
PubMed (PMID: 30273559) | 2018 | Gastroenterology (New York, N.Y. 1943)
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.
PubMed (PMID: 30254094) | 2018 | The journal of experimental medicine
Hypomorphic CARD11 mutations associated with diverse immunologic phenotypes with or without atopic disease.
PubMed (PMID: 30170123) | 2018 | Journal of allergy and clinical immunology
High-Resolution HLA-Typing by Next-Generation Sequencing of Randomly Fragmented Target DNA.
PubMed (PMID: 29858802) | 2018 | Methods in molecular biology (Clifton, N.J.)
1,000x Faster Than PLINK: Genome-Wide Epistasis Detection with Logistic Regression Using Combined FPGA and GPU Accelerators
PubMed (PMID: 10) | 2018 | Unknown Journal
ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.
PubMed (PMID: 29472497) | 2018 | The journal of experimental medicine
The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
PubMed (PMID: 29560122) | 2018 | Oncotarget
Rates of Mutation and Recombination in Siphoviridae Phage Genome Evolution over Three Decades
PubMed (PMID: 0) | 2018 | Molecular biology and evolution
The genomic history of southeastern Europe.
PubMed (PMID: 29466330) | 2018 | Nature : a weekly illustrated journal of science
Increased prevalence of rare sucrase-isomaltase (SI) pathogenic variants in irritable bowel syndrome patients.
PubMed (PMID: 29408290) | 2018 | Clinical gastroenterology and hepatology the official clinical practice journal of the American Gastroenterological Association
Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine.
PubMed (PMID: 29439003) | 2018 | BMJ open
Whither systems medicine?
PubMed (PMID: 29497170) | 2018 | Experimental & molecular medicine
IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.
PubMed (PMID: 29498923) | 2018 | Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Specific synbiotics in early life protect against diet-induced obesity in adult mice.
PubMed (PMID: 29460474) | 2018 | Diabetes, obesity & metabolism
Epidermal lipid composition, barrier integrity and eczematous inflammation are associated with skin microbiome configuration.
PubMed (PMID: 29421277) | 2018 | Journal of allergy and clinical immunology
The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany.
PubMed (PMID: 29458422) | 2018 | Microbiome
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
PubMed (PMID: 29273807) | 2018 | Nature genetics
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
PubMed (PMID: 29315334) | 2018 | PLoS medicine / Public Library of Science
Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition.
PubMed (PMID: 29331942) | 2018 | Gut : journal of the British Society of Gastroenterology
Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3.
PubMed (PMID: 29339726) | 2018 | Nature communications
A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.
PubMed (PMID: 29346566) | 2018 | Human molecular genetics
Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
PubMed (PMID: 29377952) | 2018 | PLoS medicine / Public Library of Science
Metaorganisms in extreme environments: do microbes play a role in organismal adaptation?
PubMed (PMID: 29599012) | 2018 | Zoology (Jena, Germany)
The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
PubMed (PMID: 0) | 2018 | Oncotarget
CD137+CD154- Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures.
PubMed (PMID: 29467769) | 2018 | Frontiers in immunology
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.
PubMed (PMID: 29930244) | 2018 | Nature communications
Quantifying cell free DNA in urine: comparison between commercial kits, impact of gender and inter-individual variation.
PubMed (PMID: 29793362) | 2018 | BioTechniques the international journal of life science methods Protocol guide
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
PubMed (PMID: 29549330) | 2018 | Nature genetics
Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis.
PubMed (PMID: 29572931) | 2018 | Annals of neurology
Serum anti-glycan-antibodies in relatives of patients with inflammatory bowel disease.
PubMed (PMID: 29596443) | 2018 | PloS one
Female-specific Association Between Variants on Chromosome 9 and Self-reported Diagnosis of Irritable Bowel Syndrome.
PubMed (PMID: 29626450) | 2018 | Gastroenterology (New York, N.Y. 1943)
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.
PubMed (PMID: 29653584) | 2018 | Genome medicine
Small ncRNA-Seq Results of Human Tissues: Variations Depending on Sample Integrity.
PubMed (PMID: 29691221) | 2018 | Clinical chemistry
Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals.
PubMed (PMID: 29729943) | 2018 | Journal of allergy and clinical immunology
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease.
PubMed (PMID: 29730603) | 2018 | Gut : journal of the British Society of Gastroenterology
Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum.
PubMed (PMID: 29764499) | 2018 | Microbiome
Involvement of SPATA31 copy number variable genes in human lifespan.
PubMed (PMID: 29676996) | 2018 | Aging
Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans.
PubMed (PMID: 29717136) | 2018 | Nature communications
Neolithic and Medieval virus genomes reveal complex evolution of hepatitis B.
PubMed (PMID: 29745896) | 2018 | eLife
Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.
PubMed (PMID: 29746563) | 2018 | PLoS pathogens / Public Library of Science
Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.
PubMed (PMID: 29651131) | 2018 | Scientific Reports
Analysis of Genes Associated with Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's disease.
PubMed (PMID: 29501442) | 2018 | Gastroenterology (New York, N.Y. 1943)
NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia.
PubMed (PMID: 29334255) | 2018 | Epigenomics