Publications

Institut für Klinische Molekularbiologie der Christian-Albrechts-Universität zu Kiel

2021

Genetic variability of immune-related lncRNAs: polymorphisms in LINC-PINT and LY86-AS1 are associated with pemphigus foliaceus susceptibility.
PubMed (PMID: 33394553) | 2021 | Experimental dermatology
Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T-cell memory formation after mild COVID-19 infection.
PubMed (PMID: 33399535) | 2021 | eLife
Large-scale association analyses identify host factors influencing human gut microbiome composition.
PubMed (PMID: 33462485) | 2021 | Nature genetics
Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome.
PubMed (PMID: 33462482) | 2021 | Nature genetics
Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice.
PubMed (PMID: 32987028) | 2021 | Journal of hepatology : the journal of the European Association for the Study of the Liver
Genome-wide study of a Neolithic Wartberg grave community reveals distinct HLA variation and hunter-gatherer ancestry.
PubMed (PMID: 33495542) | 2021 | Communications biology
Exome-wide association study identifies FN3KRP and PGP as new candidate longevity genes.
PubMed (PMID: 33491046) | 2021 | The journals of gerontology / Series A
Quantifying sequencing error and effective sequencing depth of liquid biopsy NGS with UMI error correction.
PubMed (PMID: 33512245) | 2021 | BioTechniques the international journal of life science methods Protocol guide
Decreased inflammatory cytokine production of antigen-specific CD4<sup>+</sup> T cells in NMDA receptor encephalitis.
PubMed (PMID: 33442772) | 2021 | Journal of neurology
Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations.
PubMed (PMID: 33555323) | 2021 | Human molecular genetics
Deciphering a Marine Bone-Degrading Microbiome Reveals a Complex Community Effort.
PubMed (PMID: 33563781) | 2021 | mSystems
Microbial Butyrate Synthesis Indicates Therapeutic Efficacy of Azathioprine in IBD Patients.
PubMed (PMID: 32687146) | 2021 | Journal of Crohn's & colitis : international journal devoted to inflammatory bowel diseases
Phylogeography in an "oyster" shell provides first insights into the genetic structure of an extinct Ostrea edulis population.
PubMed (PMID: 33504886) | 2021 | Scientific Reports
Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients.
PubMed (PMID: 33622974) | 2021 | Science immunology
Therapeutic IL-6 trans-signalling inhibition by olamkicept (sgp130Fc) in patients with active inflammatory bowel disease.
PubMed (PMID: 33667488) | 2021 | Gastroenterology (New York, N.Y. 1943)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
PubMed (PMID: 33634751) | 2021 | Autophagy
The role of cGAS/STING in intestinal immunity.
PubMed (PMID: 33577080) | 2021 | European journal of immunology
Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
PubMed (PMID: 33579932) | 2021 | Nature communications
Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
PubMed (PMID: 33585804) | 2021 | iScience
Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia.
PubMed (PMID: 33462395) | 2021 | Nature cell biology
Primate phageomes are structured by superhost phylogeny and environment.
PubMed (PMID: 33876746) | 2021 | Proceedings of the National Academy of Sciences of the United States of America
Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.
PubMed (PMID: 33888516) | 2021 | Gut : journal of the British Society of Gastroenterology
Rapid T cell receptor interaction grouping with ting.
PubMed (PMID: 33983394) | 2021 | Bioinformatics
Flow Cytometric Characterization of Human Antigen-Reactive T-Helper Cells.
PubMed (PMID: 33928550) | 2021 | Methods in molecular biology (Clifton, N.J.)
First manifestation of adult-onset Still's disease after COVID-19.
PubMed (PMID: 33817663) | 2021 | The Lancet. Rheumatology
TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels.
PubMed (PMID: 33991015) | 2021 | Alzheimer's & dementia
Host traits, lifestyle and environment are associated with the human skin bacteria.
PubMed (PMID: 33733457) | 2021 | The British journal of dermatology
Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease.
PubMed (PMID: 33930606) | 2021 | Cellular and molecular gastroenterology and hepatology
Carrying asymptomatic gallstones is not associated with changes in intestinal microbiota composition and diversity but cholecystectomy with significant dysbiosis.
PubMed (PMID: 33758296) | 2021 | Scientific Reports
Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model.
PubMed (PMID: 33717182) | 2021 | Frontiers in immunology
Mass burial genomics reveals outbreak of enteric paratyphoid fever in the Late Medieval trade city Lübeck.
PubMed (PMID: 33997698) | 2021 | iScience
Short-term physical exercise impacts on the human holobiont obtained by a randomised intervention study.
PubMed (PMID: 34078289) | 2021 | BMC microbiology
Analysis of SARS-CoV-2 RT-qPCR Ct values vis-à-vis anti-SARS-CoV-2 antibodies from a high incidence region.
PubMed (PMID: 34273511) | 2021 | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Blood group AB increases risk for surgical necrotizing enterocolitis and focal intestinal perforation in preterm infants with very low birth weight.
PubMed (PMID: 34215818) | 2021 | Scientific Reports
A 5,000-year-old hunter-gatherer already plagued by Yersinia pestis.
PubMed (PMID: 34192537) | 2021 | Cell reports
Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis.
PubMed (PMID: 34177931) | 2021 | Frontiers in immunology
The alternative serotonin transporter promoter P2 impacts gene function in females with irritable bowel syndrome.
PubMed (PMID: 34165249) | 2021 | Journal of cellular and molecular medicine
Identifying genetic modifiers of age-associated penetrance in X-linked dystonia-parkinsonism.
PubMed (PMID: 34050153) | 2021 | Nature communications
MRI-Based Iron Phenotyping and Patient Selection for Next-Generation Sequencing of Non-Homeostatic Iron Regulator Hemochromatosis Genes.
PubMed (PMID: 34048062) | 2021 | Hepatology : official journal of the American Association for the Study of Liver Diseases
Identification of two novel bullous pemphigoid- associated alleles, HLA-DQA1*05:05 and -DRB1*07:01, in Germans.
PubMed (PMID: 34011352) | 2021 | Orphanet journal of rare diseases : an online journal published by BioMed Central
BIGwas: Single-command quality control and association testing for multi-cohort and biobank-scale GWAS/PheWAS data.
PubMed (PMID: 34184051) | 2021 | GigaScience
Ancient DNA Study in Medieval Europeans Shows an Association Between HLA-DRB1*03 and Paratyphoid Fever.
PubMed (PMID: 34335597) | 2021 | Frontiers in immunology