Publications

Institut für Klinische Molekularbiologie der Christian-Albrechts-Universität zu Kiel

2018

A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention.
PubMed (PMID: 30153653) | 2018 | Aging
Serum anti-glycan-antibodies in relatives of patients with inflammatory bowel disease.
PubMed (PMID: 29596443) | 2018 | PloS one
Female-specific Association Between Variants on Chromosome 9 and Self-reported Diagnosis of Irritable Bowel Syndrome.
PubMed (PMID: 29626450) | 2018 | Gastroenterology (New York, N.Y. 1943)
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.
PubMed (PMID: 29653584) | 2018 | Genome medicine
Small ncRNA-Seq Results of Human Tissues: Variations Depending on Sample Integrity.
PubMed (PMID: 29691221) | 2018 | Clinical chemistry
Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals.
PubMed (PMID: 29729943) | 2018 | Journal of allergy and clinical immunology
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease.
PubMed (PMID: 29730603) | 2018 | Gut : journal of the British Society of Gastroenterology
Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum.
PubMed (PMID: 29764499) | 2018 | Microbiome
Involvement of SPATA31 copy number variable genes in human lifespan.
PubMed (PMID: 29676996) | 2018 | Aging
Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans.
PubMed (PMID: 29717136) | 2018 | Nature communications
Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis.
PubMed (PMID: 29572931) | 2018 | Annals of neurology
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
PubMed (PMID: 29549330) | 2018 | Nature genetics
RNA based individualized drug selection in breast cancer patients without patient-matched normal tissue.
PubMed (PMID: 30190792) | 2018 | Oncotarget
Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.
PubMed (PMID: 30089902) | 2018 | Nature : a weekly illustrated journal of science
Linear isoforms of the long noncoding RNA CDKN2B-AS1 regulate the c-myc-enhancer binding factor RBMS1.
PubMed (PMID: 30108282) | 2018 | European journal of human genetics
The Iceman's Last Meal Consisted of Fat, Wild Meat, and Cereals.
PubMed (PMID: 30017480) | 2018 | CB : current biology : dispatches from the front lines of biology
On a Western diet, APOEɛ4 is associated with low innate immune sensing, but not APOEɛ3.
PubMed (PMID: 29928926) | 2018 | Journal of allergy and clinical immunology
High-Resolution HLA-Typing by Next-Generation Sequencing of Randomly Fragmented Target DNA.
PubMed (PMID: 29858802) | 2018 | Methods in molecular biology (Clifton, N.J.)
1,000x Faster Than PLINK: Genome-Wide Epistasis Detection with Logistic Regression Using Combined FPGA and GPU Accelerators
PubMed (PMID: 10) | 2018 | Unknown Journal
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.
PubMed (PMID: 29930244) | 2018 | Nature communications
Quantifying cell free DNA in urine: comparison between commercial kits, impact of gender and inter-individual variation.
PubMed (PMID: 29793362) | 2018 | BioTechniques the international journal of life science methods Protocol guide
Neolithic and Medieval virus genomes reveal complex evolution of hepatitis B.
PubMed (PMID: 29745896) | 2018 | eLife
Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.
PubMed (PMID: 29746563) | 2018 | PLoS pathogens / Public Library of Science
Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.
PubMed (PMID: 29651131) | 2018 | Scientific Reports
Specific synbiotics in early life protect against diet-induced obesity in adult mice.
PubMed (PMID: 29460474) | 2018 | Diabetes, obesity & metabolism
Epidermal lipid composition, barrier integrity and eczematous inflammation are associated with skin microbiome configuration.
PubMed (PMID: 29421277) | 2018 | Journal of allergy and clinical immunology
The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany.
PubMed (PMID: 29458422) | 2018 | Microbiome
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
PubMed (PMID: 29273807) | 2018 | Nature genetics
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
PubMed (PMID: 29315334) | 2018 | PLoS medicine / Public Library of Science
Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition.
PubMed (PMID: 29331942) | 2018 | Gut : journal of the British Society of Gastroenterology
Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3.
PubMed (PMID: 29339726) | 2018 | Nature communications
A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.
PubMed (PMID: 29346566) | 2018 | Human molecular genetics
Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
PubMed (PMID: 29377952) | 2018 | PLoS medicine / Public Library of Science
IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.
PubMed (PMID: 29498923) | 2018 | Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Whither systems medicine?
PubMed (PMID: 29497170) | 2018 | Experimental & molecular medicine
Analysis of Genes Associated with Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's disease.
PubMed (PMID: 29501442) | 2018 | Gastroenterology (New York, N.Y. 1943)
The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
PubMed (PMID: 0) | 2018 | Oncotarget
Metaorganisms in extreme environments: do microbes play a role in organismal adaptation?
PubMed (PMID: 29599012) | 2018 | Zoology (Jena, Germany)
ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.
PubMed (PMID: 29472497) | 2018 | The journal of experimental medicine
The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
PubMed (PMID: 29560122) | 2018 | Oncotarget
Rates of Mutation and Recombination in Siphoviridae Phage Genome Evolution over Three Decades
PubMed (PMID: 0) | 2018 | Molecular biology and evolution
The genomic history of southeastern Europe.
PubMed (PMID: 29466330) | 2018 | Nature : a weekly illustrated journal of science
Increased prevalence of rare sucrase-isomaltase (SI) pathogenic variants in irritable bowel syndrome patients.
PubMed (PMID: 29408290) | 2018 | Clinical gastroenterology and hepatology the official clinical practice journal of the American Gastroenterological Association
Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine.
PubMed (PMID: 29439003) | 2018 | BMJ open
NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia.
PubMed (PMID: 29334255) | 2018 | Epigenomics