Publications

Institut für Klinische Molekularbiologie der Christian-Albrechts-Universität zu Kiel

2018

NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia.
PubMed (PMID: 29334255) | 2018 | Epigenomics
Analysis of Genes Associated with Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's disease.
PubMed (PMID: 29501442) | 2018 | Gastroenterology (New York, N.Y. 1943)
Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.
PubMed (PMID: 29651131) | 2018 | Scientific Reports
Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.
PubMed (PMID: 29746563) | 2018 | PLoS pathogens / Public Library of Science
Neolithic and Medieval virus genomes reveal complex evolution of Hepatitis B.
PubMed (PMID: 29745896) | 2018 | eLife
Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans.
PubMed (PMID: 29717136) | 2018 | Nature communications
Involvement of SPATA31 copy number variable genes in human lifespan.
PubMed (PMID: 29676996) | 2018 | Aging
Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum.
PubMed (PMID: 29764499) | 2018 | Microbiome
Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease.
PubMed (PMID: 29730603) | 2018 | Gut : journal of the British Society of Gastroenterology
Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals.
PubMed (PMID: 29729943) | 2018 | Journal of allergy and clinical immunology
Small ncRNA-Seq Results of Human Tissues: Variations Depending on Sample Integrity.
PubMed (PMID: 29691221) | 2018 | Clinical chemistry
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.
PubMed (PMID: 29653584) | 2018 | Genome medicine
Female-specific Association Between Variants on Chromosome 9 and Self-reported Diagnosis of Irritable Bowel Syndrome.
PubMed (PMID: 29626450) | 2018 | Gastroenterology (New York, N.Y. 1943)
Serum anti-glycan-antibodies in relatives of patients with inflammatory bowel disease.
PubMed (PMID: 29596443) | 2018 | PloS one
Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis.
PubMed (PMID: 29572931) | 2018 | Annals of neurology
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
PubMed (PMID: 29549330) | 2018 | Nature genetics
Quantifying cell free DNA in urine: comparison between commercial kits, impact of gender and inter-individual variation.
PubMed (PMID: 29793362) | 2018 | BioTechniques the international journal of life science methods Protocol guide
The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
PubMed (PMID: 0) | 2018 | Oncotarget
Metaorganisms in extreme environments: do microbes play a role in organismal adaptation?
PubMed (PMID: 29599012) | 2018 | Zoology (Jena, Germany)
Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
PubMed (PMID: 29377952) | 2018 | PLoS medicine / Public Library of Science
A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.
PubMed (PMID: 29346566) | 2018 | Human molecular genetics
Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3.
PubMed (PMID: 29339726) | 2018 | Nature communications
Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition.
PubMed (PMID: 29331942) | 2018 | Gut : journal of the British Society of Gastroenterology
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
PubMed (PMID: 29315334) | 2018 | PLoS medicine / Public Library of Science
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
PubMed (PMID: 29273807) | 2018 | Nature genetics
The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany.
PubMed (PMID: 29458422) | 2018 | Microbiome
Epidermal lipid composition, barrier integrity and eczematous inflammation are associated with skin microbiome configuration.
PubMed (PMID: 29421277) | 2018 | Journal of allergy and clinical immunology
IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.
PubMed (PMID: 29498923) | 2018 | Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Whither systems medicine?
PubMed (PMID: 29497170) | 2018 | Experimental & molecular medicine
Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine.
PubMed (PMID: 29439003) | 2018 | BMJ open
Increased prevalence of rare sucrase-isomaltase (SI) pathogenic variants in irritable bowel syndrome patients.
PubMed (PMID: 29408290) | 2018 | Clinical gastroenterology and hepatology the official clinical practice journal of the American Gastroenterological Association
The genomic history of southeastern Europe.
PubMed (PMID: 29466330) | 2018 | Nature : a weekly illustrated journal of science
Rates of Mutation and Recombination in Siphoviridae Phage Genome Evolution over Three Decades
PubMed (PMID: 0) | 2018 | Molecular biology and evolution
The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
PubMed (PMID: 29560122) | 2018 | Oncotarget
ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.
PubMed (PMID: 29472497) | 2018 | The journal of experimental medicine
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.
PubMed (PMID: 29930244) | 2018 | Nature communications