Genetic markers associated with long term cardiovascular outcome in kidney transplant recipients.

Authors:
Hege K Pihlstrøm, Geir Mjøen, Sören Mucha, Andre Franke, Alan Jardine, Bengt Fellström, Dag Olav Dahle, Hallvard Holdaas, Espen Melum
Year of publication:
2018
Volume:
-
Issue:
-
Issn:
1600-6135
Journal title abbreviated:
Am. J. Transplant.
Journal title long:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Impact factor:
6.190
Abstract:
There is a clear genetic contribution to the risk of cardiovascular diseases, and a composite genetic risk score (GRS) based on 27 single nucleotide polymorphisms (SNPs) was reported to predict risk of cardiovascular events in the general population. We aimed to evaluate this risk score in renal transplant recipients, a population with heightened cardiovascular risk, with a yet unknown genetic contribution. This article is protected by copyright. All rights reserved.