Research Highlight - Nature Reviews Rheumatology

April 7, 2016 - 10:30
New shared risk loci of five chronic inflammatory diseases, graphic: David Ellinghaus


The editors of Nature Reviews Rheumatology highlight our latest cross-phenotype research article with a short summary „Novel insights from large cross-disease study". 

In collaboration with researchers from 26 different countries, David Ellinghaus and Andre Franke, both members of the Cluster of Excellence “Inflammation at Interfaces”, have identified variants in 169 genetic regions including 27 novel loci which increase the risk for inflammatory bowel disease, primary sclerosing cholangitis, psoriasis and ankylosing spondylitis. The results of the study conducted at the Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University Kiel (CAU), and the University Medical Center Schleswig-Holstein (UKSH) have now been published in the journal Nature Genetics.

You find a more detailed summary also on the IKMB website.