Facts & Details:
Acute lymphoblastic leukemia (ALL) is a malignant disease of white blood cells in which early lymphoid precursors proliferate and replace the normal hematopoietic tissue of the bone marrow. More than 60% of patients diagnosed with ALL are children below the age of 15. The annual incidence rates of childhood ALL vary worldwide between one and four new cases per 100,000 children younger than 15. Fortunately, the therapy of ALL in childhood is quite successful, with overall cure rates of about 80% in developed countries.