The aim of this project is to create a high-resolution molecular map of longevity and age-related processes by generating multiple layers of information (i.e. transcriptome, methylation, genotype data) for different age groups (young vs. nonagenarians/centenarians). The data is produced using state-of-the-art technologies. The overlay and integration of the different layers will significantly improve our understanding of gene expression and regulation in human longevity and may lead to new hypotheses about the mechanisms that let some people survive to an age of 100 and beyond.
Funded by: European Union (INTERREG 4A programme Syddanmark-Schleswig-K.E.R.N - with funds from the European Regional Development Fund (2010-2012), EpiHealth (FP7-HEALTH-2011-278418; 2011-2015)