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Institut für Klinische Molekularbiologie der Christian-Albrechts-Universität zu Kiel

Scientist

Janina Dose

Research Projects - Scientist

Evolutionary Perspectives on Longevity

Genetic Architecture of Longevity

Research Group

Longevity Ancient DNA Research

Contact

+49 (0) 431 / 500 - 15 114

j.dose [at] ikmb.uni-kiel.de

Research Interest

Janina Dose

Main Publications

DNA methylation QTL analysis identifies new regulators of human longevity.
PubMed (PMID: 32160291) | 2020 | Human molecular genetics
Identification and characterization of two functional variants in the human longevity gene FOXO3.
PubMed (PMID: 29234056) | 2017 | Nature communications
On a Western diet, APOEɛ4 is associated with low innate immune sensing, but not APOEɛ3.
PubMed (PMID: 29928926) | 2018 | Journal of allergy and clinical immunology
Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells.
PubMed (PMID: 27130033) | 2016 | Free radical biology & medicine

Exome-wide association study identifies FN3KRP and PGP as new candidate longevity genes.
PubMed (PMID: 33491046) | 2021 | The journals of gerontology / Series A
Genome-wide study of a Neolithic Wartberg grave community reveals distinct HLA variation and hunter-gatherer ancestry.
PubMed (PMID: 33495542) | 2021 | Communications biology
A meta-analysis of genome-wide association studies identifies multiple longevity genes.
PubMed (PMID: 31413261) | 2019 | Nature communications
Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3.
PubMed (PMID: 29339726) | 2018 | Nature communications
APOE genotype and stress response - a mini review.
PubMed (PMID: 27457486) | 2016 | Lipids in health and disease
Free Radical Scavenging and Cellular Antioxidant Properties of Astaxanthin.
PubMed (PMID: 26784174) | 2016 | International journal of molecular sciences
Dietary Tocotrienol/γ-Cyclodextrin Complex Increases Mitochondrial Membrane Potential and ATP Concentrations in the Brains of Aged Mice.
PubMed (PMID: 26301044) | 2015 | Oxidative medicine and cellular longevity
Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization-Studies in gene-targeted replacement mice.
PubMed (PMID: 25381750) | 2014 | Molecular nutrition & food research
R-α lipoic acid γ-cyclodextrin complex increases energy expenditure: a 4-month feeding study in mice.
PubMed (PMID: 24377457) | 2014 | Nutrition (Burbank, Los Angeles County, Calif.)
Beneficial effects of a 6-month dietary restriction are time-dependently abolished within 2 weeks or 6 months of refeeding-genome-wide transcriptome analysis in mouse liver.
PubMed (PMID: 23563226) | 2013 | Free radical biology & medicine
Anti-inflammatory potential of allyl-isothiocyanate--role of Nrf2, NF-(κ) B and microRNA-155.
PubMed (PMID: 21692985) | 2012 | Journal of cellular and molecular medicine

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