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Institut für Klinische Molekularbiologie der Christian-Albrechts-Universität zu Kiel

Doctoral Researcher

Malte Rühlemann

Research Group

Genetics & Bioinformatics

Contact

+49 (0) 431 / 500 - 15 132

m.ruehlemann [at] ikmb.uni-kiel.de

Supervisor

Research Interest

Malte Rühlemann

Main Publications

Application of the distance-based F test in an mGWAS investigating beta diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and three other loci.
PubMed (PMID: 28816579) | 2017 | Gut microbes
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis.
PubMed (PMID: 28604703) | 2017 | Nature medicine
Faecal microbiota profiles as diagnostic biomarkers in primary sclerosing cholangitis.
PubMed (PMID: 27216937) | 2016 | Gut : journal of the British Society of Gastroenterology
Microbiomarkers in inflammatory bowel diseases: caveats come with caviar.
PubMed (PMID: 28733278) | 2017 | Gut : journal of the British Society of Gastroenterology
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.
PubMed (PMID: 27723756) | 2016 | Nature genetics

A structured weight loss program increases gut microbiota phylogenetic diversity and reduces levels of Collinsella in obese type 2 diabetics: A pilot study.
PubMed (PMID: 31318902) | 2019 | PloS one
Alterations of the bile microbiome in primary sclerosing cholangitis.
PubMed (PMID: 31243055) | 2019 | Gut : journal of the British Society of Gastroenterology
Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms.
PubMed (PMID: 31521200) | 2019 | Microbiome
Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis.
PubMed (PMID: 31250469) | 2019 | Alimentary pharmacology & therapeutics
Editorial: gut microbial profile associated with primary sclerosing cholangitis-what is new and how do we progress from here? Authors' reply.
PubMed (PMID: 31414547) | 2019 | Alimentary pharmacology & therapeutics
Gut mycobiome of primary sclerosing cholangitis patients is characterised by an increase of Trichocladium griseum and Candida species.
PubMed (PMID: 31653787) | 2019 | Gut : journal of the British Society of Gastroenterology
Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition.
PubMed (PMID: 31399369) | 2019 | Cell host & microbe
Pseudomonas aeruginosa populations in the cystic fibrosis lung lose susceptibility to newly applied β-lactams within 3 days.
PubMed (PMID: 31355848) | 2019 | The Journal of antimicrobial chemotherapy
Epidermal lipid composition, barrier integrity and eczematous inflammation are associated with skin microbiome configuration.
PubMed (PMID: 29421277) | 2018 | Journal of allergy and clinical immunology
Functional abdominal pain and discomfort (IBS) is not associated with faecal microbiota composition in the general population.
PubMed (PMID: 29860240) | 2018 | Gut : journal of the British Society of Gastroenterology
Functions of the Microbiota for the Physiology of Animal Metaorganisms.
PubMed (PMID: 30566939) | 2018 | Journal of innate immunity
Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum.
PubMed (PMID: 29764499) | 2018 | Microbiome
Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity.
PubMed (PMID: 30391469) | 2018 | Gastroenterology (New York, N.Y. 1943)
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.
PubMed (PMID: 29880062) | 2018 | Microbiome
Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition.
PubMed (PMID: 29331942) | 2018 | Gut : journal of the British Society of Gastroenterology
Functional sequencing read annotation for high precision microbiome analysis.
PubMed (PMID: 29194524) | 2017 | Nucleic acids research
Heart failure is associated with depletion of core intestinal microbiota.
PubMed (PMID: 28772054) | 2017 | ESC Heart Failure
Beneficial Effects of a Dietary Weight Loss Intervention on Human Gut Microbiome Diversity and Metabolism Are Not Sustained during Weight Maintenance.
PubMed (PMID: 27898428) | 2016 | Obesity facts
Interdisciplinary approach towards a systems medicine toolbox using the example of inflammatory diseases.
PubMed (PMID: 27016392) | 2016 | Briefings in bioinformatics
Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis.
PubMed (PMID: 27538787) | 2016 | Scientific Reports
Vy-PER: eliminating false positive detection of virus integration events in next generation sequencing data.
PubMed (PMID: 26166306) | 2015 | Scientific Reports

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